HISTOLAB Derma Science Triple Whitening Effect Ampoule 80ml
Experience the Miracle of 3-Step Radiance: Erase, Fill, and Glow. Unveil your skin’s true potential with this Dark Spot Correcting Serum(Triple Whitening Effect Ampoule). Powered by a clinical-grade blend of 5% Niacinamide, Glutathione, and Tranexamic Acid, this high-performance serum doesn’t just brighten—it transforms. It targets deep-seated dark spots, inhibits melanin production, and restores a youthful, porcelain-like glow to dull, tired skin.

In the Korean market, skincare treatments are subdivided into three categories based on the concentration of active ingredients: Essence, Serum, and Ampoule. While ‘Essence’ is the lightest and ‘Serum’ provides medium care, ‘Ampoule’ represents the highest concentration, offering the most potent effects.
Difference Between Essence, Serum, and Ampoule
| Category | Essence | Serum | Ampoule |
|---|---|---|---|
| Traditional Use & Step | First treatment step after toner (before serum). | Targeted treatment after essence. | Highly concentrated treatment used before or instead of serum. |
| Consistency | Lightweight, watery, and less viscous. | Slightly thicker and more viscous than an essence. | Thickest and most concentrated. |
| Concentration | Moderate concentration of active ingredients. | Higher concentration of active ingredients than an essence. | Highest concentration of active ingredients. |
| Primary Purpose | To hydrate, balance skin pH, and prepare the skin to better absorb subsequent products. Foundation for treatment. | To target specific skin issues (e.g., anti-aging, dark spots, acne). Focused treatment. | To deliver a powerful boost of key ingredients for intense treatment over a short period. Booster/Intensive Treatment. |
Although this product is technically an ampoule, we will refer to it as a ‘serum‘ for customers who are unfamiliar with ampoules.
Currently, Histolab products are loved by almost 8,500 dermatological and aesthetic clinics in Korea. Thanks to its wide variety of product ranges, Histolab products have become famous for having excellent efficiencies in the field of professional peeling, acne treatment, and post-laser skin treatment as well as basic care like wrinkle improvement freckles, skin rejuvenation, whitening., etc.
Main Features
- Triple-Action Brightening System: A scientifically formulated trio of Niacinamide, Glutathione, and Tranexamic Acid works in synergy to block melanin transfer and fade pigmentation.
- High-Concentration Formula: Contains 5% Niacinamide and 3% Tranexamic Acid, exceeding standard over-the-counter levels for visible results.
- Deep Melanin Control: Systematically targets the root cause of dark spots, preventing future discoloration before it appears.
- Instant Hydration & Glow: Not only does it brighten, but it also replenishes moisture, leaving skin dewy and radiant without a sticky residue.
- Dermatologist-Grade Skincare: Developed by HISTOLAB, a trusted Korean clinical skincare brand used by professionals.
- Dual-Function Skincare for Brightening & Anti-Wrinkle
Triple-Action Brightening System
It maintains healthy skin balance while evening out and brightening your overall complexion. By simultaneously targeting dark spots, freckles, and discoloration, it delivers a comprehensive and effective whitening treatment.The “Synergy Effect” of 3 Ingredients: Most brightening serums rely on just one active ingredient.

Main Ingredients
- Glutathion(100ppm): Composed of Glutamic acid, Cysteine, and Glycine, this powerful tripeptide molecule works by blocking tyrosinase—the enzyme that triggers melanin. This action helps deliver a visible whitening effect.
- Niacinamide (5%): Whitening & Barrier Support. Blocks the transfer of melanin to the skin surface to prevent pigmentation and strengthens the skin barrier.
- Tranexamic Acid(3%): Pigment Correction. Known for its powerful ability to inhibit melanin synthesis, effectively fading stubborn dark spots and melasma.
Formulation
This dark spot correcting serum features a lightweight, nutrient-rich liquid texture that absorbs instantly into the skin. It leaves a fresh, moist finish with absolutely no stickiness or greasiness.

How to use
- Cleanse your face and apply a toner to prep your skin.
- Take an appropriate amount of the ampoule using the dropper.
- Gently apply it over your entire face, focusing on areas with dark spots.
- Lightly pat your skin with your fingertips to aid absorption.

Recommended for
- Those who are struggling with dull, uneven skin tone and want immediate brightness.
- Those who are concerned about visible freckles, blemishes, and dark spots.
- Those who want a professional-grade whitening treatment at home.
- Those who need a serum that provides both hydration and radiance without irritation.
Ingredients
Water, Glycerin, Dipropylene Glycol, Butylene Glycol, Niacinamide, Tranexamic Acid, Glyceryl-26, Propanediol, 1,2-Hexanediol, Glycosyl Trehalose, Hydroxyacetophenone, Hydrogenated Starch Hydrolysate, Tromethamine, Xanthan Gum, Carbomer, Ethylhexylglycerin, Adenosine, Disodium EDTA, Beta-Glucan, Glutathione, Polysorbate 20, Hydrolyzed Gardenia Florida Extract, Hydrolyzed Viola Tricolor Extract, Hydrolyzed Malt Extract, Lecithin, Hyaluronic Acid, Hydrolyzed Hyaluronic Acid, Sodium Hyaluronate, Nicotinoyl Hexapeptide-44, sh-Oligopeptide-1, sh-Polypeptide-4, sh-Polypeptide-16, sh-Polypeptide-1


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