Korea’s number one selling melasma cream, Taeguk Pharm Domina Cream utilizes clinically proven 4% Hydroquinone to directly target dark spots, freckles, and excessive melanin production
Fade stubborn dark spots with Korea’s #1 trusted melasma cream!

About Taeguk Pharm
The Culmination of 68 Years of Melasma Research
Taeguk Pharm is South Korea’s premier pharmaceutical brand, renowned for its unparalleled expertise in treating hyperpigmentation. With 68 years of dedicated research into melasma and skin discoloration, the brand combines advanced dermatological science with clinically proven ingredients to target the root causes of uneven skin tone.
As the creator of Domina Cream—the #1 best-selling melasma and hyperpigmentation treatment in South Korea—Taeguk Pharm has earned the deep trust of consumers seeking real, visible results. Dedicated to restoring your skin’s natural health and clarity, Taeguk Pharm provides safe, effective, and targeted solutions for a flawless, radiant complexion.
Main Features
- Clinically Proven Efficacy: Demonstrated to provide a 38.1% improvement in melasma treatment over 12 weeks of use compared to 8.3% in the control group.
- Targeted Melanin Control: Actively inhibits tyrosinase, the key enzyme responsible for excessive melanin production when the skin is exposed to UV rays.
- Comprehensive Pigment Care: Effectively treats various forms of hyperpigmentation, including melasma, sun-induced freckles, senile dark spots, and unnecessary pigmentation.
- Korea’s Top Choice: Recognized as the #1 top-selling melasma cream and hyperpigmentation treatment in South Korea.
Why does melasma occur?
The primary cause is UV rays. Melanin pigment is part of the body’s biological defense mechanism to protect against UV rays, but this process causes hyperpigmentation such as melasma. Additionally, hormonal changes due to pregnancy can also trigger melasma.

In which layer of the skin does melasma primarily occur?
It most commonly occurs in the epidermal layer. Melasma is categorized into epidermal type, dermal type, and mixed type based on where it appears, and Koreans typically have a high distribution of melanin in the epidermal layer. Furthermore, the thickness of the epidermis in Koreans is thinner (0.05mm) compared to Westerners (0.1mm).

Main Ingredients
Hydroquinone (40mg per 1g / 4%): The primary active ingredient that effectively blocks tyrosinase enzymes, stopping the overproduction of melanin and fading existing dark spots.

Skin Test
In a 12-week clinical study comparing a 4% Hydroquinone melasma cream treatment group against a control group, the 4% Hydroquinone group showed a 38.1% melasma treatment effect, whereas the control group only showed an 8.3% improvement.

Formulation
A rich, white to pale yellow cream texture that easily adheres to targeted areas of concern for optimal treatment.
How to use
- Perform a sensitivity test behind the ear or under the jaw for 24 hours prior to full application.
- Apply a small amount exclusively to the affected areas 1 to 2 times a day (morning and before bedtime).
- For evening use, apply as a spot treatment after your basic skincare routine (toner and lotion). Do not apply to the entire bare face.
- If used during the day, it is critical to avoid direct sunlight by generously applying sunscreen and using hats or parasols, though evening application is highly recommended instead.
- If applied the night before, wash your face thoroughly in the morning so no medicinal residue remains on the skin.
- Stop using if no symptom improvement is seen after 2 months (this may indicate your skin does not react to hydroquinone in this melasma cream).
- If improvement occurs, it is recommended to continue use for 3 to 4 months for sufficient results.
- Use within 6 months of opening.
Recommended for
- Those who are struggling with melasma primarily caused by UV exposure or hormonal changes during pregnancy.
- Those who want to treat visible freckles and senile dark spots.
- Those who are looking for a highly effective, clinically proven melasma cream for excessive melanin hyperpigmentation.
Ingredients
- Active Ingredient: Hydroquinone (40mg per 1g).
- Other Additives: Polyethylene Glycol 4000, Sorbitan Stearate, Edetate Disodium Hydrate, Beta-Glucan 0.3% Liquid, Cetanol, Polyethylene Glycol 400, Paraffin, Polysorbate 60, Propylene Glycol, White Beeswax, Purified Water, Cholesterol, Polyoxyethylene Cetyl Ether, Fragrance (Skincare 23538), Propyl p-Hydroxybenzoate, Tocopheryl Acetate, Aloe Vera Gel, Sodium Lauryl Sulfate, Mineral Oil, Lanolin Alcohol, Sodium Metabisulfite, Methyl p-Hydroxybenzoate, Ascorbyl Palmitate, Liquid Paraffin, Squalane, Octyldodecanol
Other Important Info
- Storage: Store in an airtight container in a cool, dry, and dark place below 30°C.
- Packaging: Available in a 60g jar or a 50g tube.
- Color Change Note: It is normal for the cream to turn slightly brown during use; this is a typical reaction of the main ingredient and is completely safe for continued use.
FAQ
- Q: What is the main cause of melasma?
A: The primary cause of melasma is UV rays, which trigger melanin production as a biological defense mechanism, leading to hyperpigmentation. Hormonal changes from pregnancy can also cause melasma. - Q: Where does melasma typically occur?
A: It most commonly occurs in the epidermal layer of the skin. - Q: How does Domina Cream work?
A: Its active ingredient, Hydroquinone, inhibits the tyrosinase enzyme to prevent the excessive production of melanin when skin is exposed to UV light. - Q: How long should I use it to see results?
A: If you see improvement after initial use, it is recommended to use it consistently for about 3 to 4 months for sufficient results.


















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