Anti wrinkle serum for those of you who envy elastic skin, this is the only wrinkle improvement serum among products produced by HISTOLAB.
EGF complex Anti wrinkle serum contains 63% of EGF Complex for potent wrinkle care. Adenosine which works as an active anti-wrinkle agent and EGF complex immensely helps improve skin’s elasticity. It is effective in soothing and moisturizing the skin.
Unlike other countries, in Korea, serums are called by different names depending on their concentration, such as essence, serum, and ampoule.
- Essence: Light, watery. Lower concentration. Hydrates and preps skin for better absorption. Used after toner.
- Serum: More viscous, concentrated. Higher concentration. Targets specific skin concerns (wrinkles, whitening, etc.). Used after essence, before cream.
- Ampoule: Highly concentrated, potent. Highest concentration. Intensive, short-term treatment for specific issues. Used after essence/serum or can replace it.
About HISTOLAB
HISTOLAB is a leading K-beauty professional skincare brand, trusted by nearly 8,500 dermatological and aesthetic clinics in Korea. Renowned for its high-performance formulas, HISTOLAB offers specialized solutions for professional peeling, acne treatment, and post-laser recovery. This 63% EGF concentrate provides intensive skin rejuvenation and elasticity. Available exclusively at professional dermatology clinics and medical centers across Korea.“

The only serum for wrinkles improvement of HISTOLAB!
Main Features:
- Functional cosmetic for anti-wrinkle: A functional ampoule containing Adenosine for wrinkle improvement, an ingredient notified by KFDA.
- SRGF H1 Complex: Contains Medians’s own patent-applied ingredients (SRGF H1 Complex) to help provide a soothing and moisturizing effect.
- Skin moisturizing: Various moisturizing agents keep the skin deeply hydrated and prevent hydration evaporation for radiant skin.
- 63% of EGF Complex for potent wrinkle care effect: KFDA- listed ingredient Adenosine works as an active anti-wrinkle agent.
- Paraben-free / Alcohol-free.
Main Ingredients:
- SRGF H1 Complex: Moisturizing- soothing
- 63% EGF Complex Ampoule: Skin renewal.
- Adenosine: Anti-wrinkle.
- Trehalose: Moisturizing.
- Nasturtium Extract: Nutrition.

EGF Complex anti wrinkle serum Use Order:

How to use:
After applying toner, take 2~3 drops and apply with gentle patting.

Recommended for:
- Those who need soothing skin.
- Those who need skin protection from external trendy ingredients.
- Those who are concerned about skin vitality.
- Those who are concerned about rough and brittle skin.
Differences between 4 types of Histolab ampoules:

Ingredients:
Water, Butylene Glycol, Glycerin, 1,2-Hexanediol, Eclipta Prostrata Extract, Trehalose, Biosaccharide Gum-1, Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Arginine, Methyl Methacrylate Crosspolymer, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Isohexadecane, Allantoin, Polysorbate 80, Xanthan Gum, Sodium Chondroitin Sulfate, Polysorbate 20, Adenosine, Lavandula Angustifolia (Lavender) Oil, Disodium EDTA, Lecithin, Sorbitan Oleate, sh-Oligopeptide-1(0.25ppm), sh-Polypeptide-1, sh-Polypeptide-16, sh-Polypeptide-4, Nicotinoyl Hexapeptide-44
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necholas –
Those who need skin protection from external trendy ingredients, it will be useful
philiphia –
good product
using it will be good
Sarah M. –
It has great absorption and provides amazing moisture care. I bought one for my mom after trying it myself.
chloevan94 –
It keeps my skin so beautifully plump and hydrated that I¡¯ve been using this exact product for several years now.
Megan_T –
I purchased this after loving the sample. It has a slightly viscous texture, but it absorbs beautifully and leaves the skin so hydrated. I¡¯m currently getting laser toning treatments at a skin clinic, so this is going to be amazing for skin regeneration.
amanda_r –
This is a high-quality ampoule that absorbs deeply into the skin without leaving any greasy or floating residue on the surface.
Barbara L. –
I apply this ampoule right after washing my face and before using my toner. Thanks to the EGF ingredient, the tiny bumps and texture irregularities on my skin are noticeably improving.
jennifer –
My sensitive, breakout-prone skin has improved so much! That¡¯s why I keep using it consistently.
Jessie M. –
Pairing this EGF ampoule with my beauty device creates a gorgeous inner glow, and my skin stays completely free from dryness all through the next day.
Emily W. –
When I apply this ampoule before bed, my skin feels noticeably less dry and stripped in the morning.
daniel_m –
When my skin barrier completely broke down and my face was all red and stinging, I tried so many products. I stumbled upon this ampoule, and it had such an incredible soothing effect that I¡¯ve been using only this ever since.
Jessica D. –
It absorbs gently and smoothly, leaving my skin feeling beautifully sleek and soft to the touch.
matt_jones –
Almost no skincare products work for my skin type, but this ampoule is the only one that genuinely fits me perfectly. I¡¯m so happy.